EGCG Metal–Polyphenol Frameworks for Controlling Nitric Oxide Release in the Treatment of MRSA-Infected Wounds

, encapsulating the GSNO. The results demonstrated that under 808 nm laser irradiation, the photothermal-triggered release of NO could inhibit MRSA and eliminate biofilms. EGCG has the ability to scavenge ROS and inhibit inflammation, effectively inducing macrophage polarization from M1 to M2, promoting angiogenesis and wound healing. In summary, this work designed a simple and effective drug delivery system, providing a promising therapeutic strategy for controlling MRSA infection and promoting tissue regeneration.