获得性免疫系统
NF-κB
先天免疫系统
细胞命运测定
免疫系统
生物
B细胞
细胞生物学
免疫学
信号转导
转录因子
遗传学
抗体
基因
作者
Caitlyn Guldenpfennig,Emma Teixeiro,Mark A. Daniëls
标识
DOI:10.3389/fimmu.2023.1214095
摘要
NF-κB signaling is essential to an effective innate and adaptive immune response. Many immune-specific functional and developmental outcomes depend in large on NF-κB. The formidable task of sorting out the mechanisms behind the regulation and outcome of NF-κB signaling remains an important area of immunology research. Here we briefly discuss the role of NF-κB in regulating cell fate decisions at various times in the path of B cell development, activation, and the generation of long-term humoral immunity.
科研通智能强力驱动
Strongly Powered by AbleSci AI