Correlation Between Prefrontal Functional Connectivity and the Degree of Cognitive Impairment in Alzheimer’s Disease: A Functional Near-Infrared Spectroscopy Study

These results suggest that the left dorsolateral PFC may be the key cortical impairment in AD. Furthermore, there are different resting-state prefrontal network patterns in AD continuum, and the degree of cognitive impairment is positively correlated with reduced FC strength.