Covalent triazine framework-1: A novel oxidase and peroxidase mimic

A triazine-based covalent organic framework, CTF-1, for the first time, was found to possess both intrinsic peroxidase-like activity and oxidase-like activity and be capable to catalyze the oxidation of chromogenic substrates with or without H2O2 with high efficiency as a robust catalyst. Related oxidization mechanism was thoroughly studied, and the according catalytic properties of CTF-1 was also evaluated. What's more, a facile and effective colorimetric assay was established to detect biothiols without using any oxidizing agents. Compared to natural enzymes and other reported artificial enzymes, CTF-1 has also demonstrated the advantages including low cost, easy preparation, good stability, and high catalytic activity, which made it a very promising enzyme-mimetic alternative in potential applications in biosensors for the future.