Effects of subclinical hypothyroidism on pregnancy outcome and offspring development

The metabolism of thyroid hormone changes during pregnancy. Subclinical hypothyroidism during pregnancy may adversely affect the pregnancy outcomes and neuropsychological development of child, controversially. The diagnostic criteria of subclinical hypothyroidism during pregnancy need to be specific. It is important to figure out when should pregnancy with subclinical hypothyroidism be treated and what is the specific goal of the treatment. (Chin J Endocrinol Metab, 2017, 33: 269-272) Key words: Pregnancy; Subclinical hypothyroidism; Pregnancy outcome; Offspring development