Efficacy of pelvic floor muscle training in the management of premature ejaculation: a systematic review and meta-analysis of randomized controlled trials

医学 随机对照试验 盆底肌 物理疗法 早泄 盆底 荟萃分析 心理干预 生物反馈 科克伦图书馆 物理医学与康复 严格标准化平均差 佩萨 射精 性功能障碍 梅德林 临床试验 康复 系统回顾 肌电图 妇科 随机化
作者
Felipe Andrade de Oliveira,Lisleia Brito Lima,Matheaus Oliveira da Costa,Silvana Maria de Macêdo Uchôa,Juliana Lenzi,Guilherme Pertinni de Morais Gouveia
出处
期刊:The Journal of Sexual Medicine [Elsevier BV]
卷期号:23 (6)
标识
DOI:10.1093/jsxmed/qdag131
摘要

BACKGROUND: Premature ejaculation (PE) is a prevalent sexual dysfunction (5%-15%), and pelvic floor muscle training (PFMT) has been proposed as a non-pharmacological alternative to improve intravaginal ejaculatory latency time (IELT). AIM: To evaluate the efficacy of PFMT in the management of PE through a systematic review and meta-analysis of randomized controlled trials. METHODS: Randomized controlled trials involving men diagnosed with PE were included, searched in CINAHL, Clinical Trials, CENTRAL, Embase, MEDLINE, PEDro, SciELO, Scopus, and Web of Science up to October 2025, with no restrictions on time or language. The Rayyan software was used for study screening, and risk of bias was assessed using the Cochrane Risk of Bias 2.0 tool by 2 independent reviewers (F.A.O. and L.B.L.) Statistical analysis was performed using Review Manager 5 with a random-effects model. The primary outcome was IELT, which was reported as both mean and median, and the estimated values were standardized for the meta-analysis. Sensitivity analysis evaluated the impact of heterogeneity and risk of bias on the effect of PFMT. OUTCOMES: Five studies were included in this review and assessed in the meta-analysis. A total of 236 men participated in the studies, and 216 were randomized across the groups included in the meta-analysis. Pelvic floor muscle training and sphincter control training (SCT) showed a smaller effect on IELT compared with control interventions using dapoxetine or combined therapies, with mean differences of -54.09 s (95% CI [-92.13, -16.05]) and -81.44 s (95% CI [-127.54, -35.34]), respectively. Heterogeneity was considered high in the PFMT subgroup (I2 = 75%) and null for the SCT subgroup (I2 = 0%). CONCLUSION: Dapoxetine or the combination of PFMT with an auxiliary masturbation device or diaphragmatic breathing exercises may be superior in improving IELT in men with PE compared with isolated exercise programs.
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