In silico comparative study of epitopes predicted from different strains of genus parvovirus.

Parvoviruses are typically linear, non-segmented single-stranded DNA viruses, with an average genome size of 5000 nucleotides. Parvoviruses are some of the smallest viruses found in nature. Some have been found as small as 23 nm. Many types of mammalian species have a strain of parvovirus associated with them. Parvoviruses tend to be specific about the taxon of animal they will infect, but this is a somewhat flexible characteristic. Thus, all strains of parvovirus will affect dogs, wolves, and foxes, but only some of them will infect human. Parvovirus is treated with the help of vaccines but the traditional vaccine development process is very expensive and unsafe, with the help of insilico software tools and databases we can predict the epitopes of parvovirus species such as Canine parvovirus, Feline panleukopenia virus, H-1 virus, LUIII virus, Mink enteritis virus, Minute virus of mice, Porcine parvovirus, Raccoon parvovirus, by using Bepipred, CTLpred. These predictions will be useful for reverse vaccinology against parvoviruses infections for cattle and mankind.