Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions
作者
Ellen M. Sletten,Rachael A. Day,Daniel A. Estabrook,Jessica K. Logan
出处
期刊:日期:2017-01-01
标识
DOI:10.26434/chemrxiv.5382781
摘要
<p>Photodynamic therapy (PDT) requires photosensitizer, light, and oxygen to induce cell death. The majority of efforts to advance PDT focus only on the first two components. Here, we employ perfluorocarbon nanoemulsions to simultaneously deliver oxygen and photosensitizer. We find that the implementation of fluorous soluble photosensitizers enhances the efficacy of PDT. </p>