自愈水凝胶
丝素
脚手架
伤口愈合
材料科学
伤口敷料
炎症
纳米技术
生物医学工程
医学
免疫学
高分子化学
丝绸
复合材料
作者
Yuna Qian,Yujing Zheng,Juan Jin,Xuan Wu,Kejia Xu,Mali Dai,Qiang Niu,Hui Zheng,Xiaojun He,Jianliang Shen
标识
DOI:10.1002/adma.202200521
摘要
-induced self-assembled GA and photo-crosslinked methyl acrylated silk fibroin (SF), realizing both excellent injectability and mechanical strength. Notably, the SF/GA/Zn hybrid hydrogel can regulate macrophage responses in the inflammatory microenvironment, circumventing the use of any additives. The immunomodulatory properties of the hydrogel can be harnessed for safe and efficient therapeutics that accelerate the three phases of wound repair and serve as a promising dressing for the management of diabetic wounds.
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