A review on processing methods and functions of wheat germ-derived bioactive peptides

生物技术 小麦胚芽 生物安全 生化工程 生物 功能性食品 生物利用度 计算生物学 生物化学 生物信息学 食品科学 工程类
作者
Zebin Weng,Yuanrong Chen,Tingting Liang,Yajuan Lin,Hui Cao,Haizhao Song,Ling Xiong,Fang Wang,Xinchun Shen,Jianbo Xiao
出处
期刊:Critical Reviews in Food Science and Nutrition [Informa]
卷期号:63 (22): 5577-5593 被引量:11
标识
DOI:10.1080/10408398.2021.2021139
摘要

Wheat germ protein is a potential resource to produce bioactive peptides. As a cheap, safe, and healthy nutritional factor, wheat germ-derived bioactive peptides (WGBPs) provide benefits and great potential for biomedical applications. The objective of this review is to reveal the current research status of WGBPs, including their preparation methods and biological functions, such as antibacterial, anti-tumor, immune regulation, antioxidant, and anti-inflammatory properties, etc. We also reviewed the information in terms of the preventive ability of WGBPs to treat serious infectious diseases, to offer their reference to further research and application. Opinions on future research directions are also discussed. Through the review of previous research, we find that there are still some scientific issues in the basic research and industrialization process of WGBPs that deserve further exploration. Firstly, based on current complex enzymolysis, the preparation and production of WGBPs need to be combined with other advanced technology to achieve efficient and large-scale production. Secondly, studies on the bioavailability, biosafety, and mechanism against different diseases of WGBPs need to be carried out in different in vitro and in vivo models. More human experimental evidence is also required to support its industrial application as a functional food and nutritional supplement.HighlightsThe purification and identification of wheat germ-derived bioactive peptides.The main biological activities and potential mechanisms of wheat germ hydrolysates/peptides.Possible absorption and transport pathways of wheat germ hydrolysate/peptide.Wheat germ peptide shows a variety of health benefits according to its amino acid sequence.Current food applications and future perspectives of wheat germ protein hydrolysates/peptide.
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