Reductive Amination of Carbonyl Compounds with NaBH4-H3PW12O40 in THF and Under Solvent-Free Conditions

A simple, completely chemoselective, and convenient procedure for reductive amination of aldehydes and ketones using NaBH4 in the presence of H3PW12O40 in THF and under solvent-free conditions at ambient temperature is described. Keywords: Reductive amination, H3PW12O40, NaBH4, solvent-free conditions