The clinical effect observation of combination therapy with edaravone and ozagrel for acute cerebral infarction

Objective To observate and discuss the clinical effect of combination therapy with edaravone and ozagrel for acute cerebral infarction, as to find a better therapy to treat apoplectics. Methods The case-control trail was carried out. 283 inpatients of acute cerebral infarction were randomly divided into three groups ,including edaravone group, ozagrel group and combination therapy group. The index included National Institutes of Health Stroke (NIHSS) and Barthel exponent of different time (day 7, dayl4, day21). Results NIHSS was significantly decreased in the combination therapy group compared with single therpy groups and Barthel exponent was increased after 14 day the patients inpatiented. Conclusions The combination therapy was evidently better than the single treatments either edaravone or ozagrel, which is worthwhile to spread around.