Postoperative enterocutaneous fistula is a very serious problem in abdominal surgery. Here in we report a case successfully treated for enterocutaneous fistula with two layer local flaps. Under a diagnosis of ascending colon cancer, a 78-year-old man had undergone right hemicolectomy and resection of the involved ileum and abdominal wall. On the 10th postoperative day, enterocutaneous fistula occurred at the midline incision. Although we tried various conservative treatments, the fistula had not closed six months after the first operation. Thus, we decided to attempt operative treatment. Under local anesthesia, the fistula was closed with a “donor flap”, and the new skin defect was covered with a “rhomboid flap”. Using these two layer local flaps, fistula closure was achieved, and the patient was discharged without fistula recurrence.