Glucose oxidase is a kind of green,safe,non-toxic side effects of feed additives. It can significantlyimprove the intestinal microecological balance and animal intestinal digestion environment,protect the intestinalhealth,improve the utilization rate of feed and promote animal growth and enhancing animal body resistance. Microbi-al mold has the advantages of sources and short growth cycle,which is widely used in industrial production of glucoseoxidase. In this paper,the production of glucose oxidase and application in feed industry were reviewed.