Chemical Constituents from the Stems of Cassava (Manihot esculenta) in Hainan

Six compounds were isolated from the EtOH extract of Manihot esculenta(cassava) stems.On the basis of spectral data,they were identified as furan(1),ceplignan(2),indole-3-carboxylic acid(3),3,9,13-megastigmanetriol(4),amentoflavone(5) and yucalexin P-21(6).Compounds 1-5 were obtained from cassava for the first time.Antibacterial activity was assayed by paper disk diffusion method,and compounds 1,3,4,and 6 showed inhibitory activity against methicillin-resistant Staphylococcus aureus(MRSA) and S.aureus.