Velvet antler for healthcare has a long history and wide application. Velvet has complex chemical composition and widely pharmacological activities. The chemical constituents and pharmacological activities of antler were reviewed in this paper. The chemical ingredients of velvet antler include inorganic elements, proteins, peptides, amino acids, lipids, polyamine compounds,vitamins,steroids,polysaccharides,nucleic acids,base components. Velvet antler has a certain effect on the reproductive system,immune system,cardiovascular system,antioxidant and anti-aging,anti-fatigue,anti tumor,nervous system,anti-stress,liver,tissue wound healing,osteoporosis,lose weight and lipid-lowering.