纳米孔
材料科学
检出限
碳纳米管
适体
合金
选择性
纳米颗粒
电极
电化学
胶体金
纳米技术
纳米复合材料
复合数
化学工程
色谱法
化学
冶金
复合材料
催化作用
有机化学
物理化学
工程类
生物
遗传学
作者
Yan Sheng Yin,Xiaoli Qin,Qianchao Wang,Yin Yin
出处
期刊:RSC Advances
[The Royal Society of Chemistry]
日期:2016-01-01
卷期号:6 (45): 39401-39408
被引量:31
摘要
A facile electrochemical aptasensor based on a novel signal amplification strategy was employed for sensitive and selective detection of streptomycin for the first time. The aptasensor was prepared by sequentially dripping a gold nanoparticle-functionalized magnetic multi-walled carbon nanotube (Au@MWCNTs–Fe3O4) composite and nanoporous PtTi (NP-PtTi) alloy onto a glassy carbon electrode (GCE) surface. The NP-PtTi alloy with a uniform nanoporous structure was successfully fabricated by selectively de-alloying Al from a PtTiAl alloy in HCl solution. The results demonstrated that the Au@MWCNTs–Fe3O4/NP-PtTi composite not only showed a remarkable synergistic effect towards the aptasensor, but also provided a beneficial immobilization platform for the streptomycin aptamer carrier. Under optimal conditions, a wide linear range from 0.05 to 100 ng mL−1 and a detection limit of 7.8 pg mL−1 were obtained. The designed aptasensor showed an excellent analytical performance with good reproducibility, high selectivity and stability. Finally, the proposed aptasensor was successfully used for the detection of streptomycin in a real sample.
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