Improved growth curve measurements after supraglottoplasty

喉软化 医学 百分位 增长曲线(统计) 曲线下面积 外科 回顾性队列研究 内科学 震颤 统计 气道 经济 计量经济学 数学
作者
Jeremy D. Meier,Shaun A. Nguyen,David R. White
出处
期刊:Laryngoscope [Wiley]
卷期号:121 (7): 1574-1577 被引量:23
标识
DOI:10.1002/lary.21865
摘要

Abstract Objectives/Hypothesis: To evaluate changes in growth curve measurements after supraglottoplasty and compare these patterns to patients with laryngomalacia treated conservatively. Study Design: Retrospective case–control study. Methods: Children treated surgically for laryngomalacia were compared to control groups of patients who underwent observation or medical treatment only. Body weight the day of surgery and on follow‐up visits was plotted on a standardized growth curve and the z ‐score calculated. Results: A total of 15 patients were included that were observed (group 1), 71 patients that were treated with medical therapy only (group 2), and 29 patients that underwent surgery (group 3). The average z ‐score at the time of surgery was significantly worse in group 3 (−0.854 ± 1.080), compared to the z ‐score at the time of diagnosis in group 1 (−0.086 ± 0.834), and the time when antireflux therapy was initiated in group 2 (−0.120 ± 0.979). Within 3 months from surgery, significant improvement on the growth curve was seen in group 3 ( P = .009). After 12 months, all three groups approached the mean on the growth curve. Conclusions: In this series, patients with severe laryngomalacia who warranted surgery presented with significantly lower percentile weight on a standardized growth curve than patients who required only medical or conservative treatment. Substantial improvement in growth curve percentile was seen in the immediate months following supraglottoplasty. Long‐term follow‐up after supraglottoplasty shows that infants return to a mean weight on the growth curve.
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