Effects of Spinal Cord Stimulation on Spasticity and Spasms Secondary to Myelopathy

医学 痉挛 脊髓 麻醉 刺激 外科 脊髓病 病变 阵挛 脊髓刺激器 脊髓损伤 腰椎 脊髓刺激 癫痫 内科学 精神科
作者
Giancarlo Barolat,Joel B. Myklebust,William Wenninger
出处
期刊:Stereotactic and Functional Neurosurgery [S. Karger AG]
卷期号:51 (1): 29-44 被引量:60
标识
DOI:10.1159/000099381
摘要

16 subjects with severe spasms secondary to traumatic and nontraumatic myelopathy underwent epidural spinal cord stimulation. 4 patients had a complete motor and sensory spinal cord lesion. 6 of the subjects with an incomplete spinal cord lesion were ambulatory. All patients had previously undergone extensive trials with medications and physical therapy. All 14 subjects in whom a satisfactory placement of the elec-trode could be obtained had a reduction in the severity of the spasms. In 6 patients, the spasms were almost abolished. Extremity, trunkal and abdominal spasms were affected. Clonus in the upper extremities was consistently reduced. Marked improvement in bladder and bowel function was observed in each of 2 subjects. In over 1-year follow-up, 5 subjects show persistence of the results, with less stimulation required to maintain the therapeutic effects. No neurological deterioration occurred following the procedure or after long-term spinal stimulation. 1 patient showed after several months of continuous stimulation increased voluntary motor control present only when spinal cord stimulation was activated. Complications included 1 system infection, 1 electrode migration, 1 wire breakage and skin breakdown at a connector site, development of high impedance in 1 electrode and 1 skin breakdown over the lead.
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