Surface-enhanced Raman spectroscopy for medical diagnostics and bio-imaging

S Enhanced Raman Spectroscopy (SERS) is one of the most valuable analytical which has the ability for ultra-sensitive biochemical sensing and providing its chemical fingerprint. In this lecture we will discuss our recent reports on how SERS can be used for model diagnostics as well as for bio-imaging. Our reported data demonstrated that bio-conjugated nanomaterial base SERS can be used for the ultra-sensitive detection of cancer & different multiple drug resistance bacteria. We have also shown that SERS base optical ruler can be used to monitor drug delivery, photothermal therapy response etc. Here we will discuss first the basic science behind surface enhanced spectroscopy and then it’s working principle for medical diagnostics. Next we will discuss SERS applications in biology, medicine, and enviromental science. Finally, we will conclude by speculating about future scientific research and challenges in technological applications of SERS. Paresh Chandra Ray, J Anal Bioanal Tech 2013, 4:5 http://dx.doi.org/10.4172/2155-9872.S1.013