异香豆素
红树林
青霉属
真菌
立体化学
化学
抗氧化剂
圆二色性
异香豆素类
IC50型
植物
生物
有机化学
生物化学
食品科学
体外
生态学
催化作用
作者
Wei-Nv Zeng,Jin Cai,Bin Wang,Liang-Yu Chen,Chen-Xin Pan,Shi-Ji Chen,Guo-Lei Huang,Cai-Juan Zheng
标识
DOI:10.1080/10286020.2021.1952188
摘要
A new isocoumarin, penicimarin N (1), along with five known compounds (2-6), were isolated from the mangrove-derived fungus Penicillium sp. TGM112. The structure of 1 was elucidated on the basis of extensive spectroscopic data analysis, and the absolute configuration of 1 was determined by comparison of their circular dichroism (CD) spectra with the literature. The structures of known compounds were determined by comparison with the literature data. All the isolated compounds were examined for their antioxidant and α-glucosidase activities. Compound 1 showed strong antioxidant activity with the IC50 value of 1.0 mM, and 1 also exhibited moderate inhibitory activity against α-glucosidase with the IC50 value of 620 μM.
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