Pro‐inflammatory cytokine interleukin‐6‐induced hepcidin, a key mediator of periodontitis‐related anemia of inflammation

Systemic inflammation induced by periodontitis leads to an increased risk for AI. IL-6-induced hepcidin could play a central mediator role and act as a key pathologic mechanism. Our results demonstrate periodontitis may be considered as an additional inflammatory disease contributing to the development of AI.