Stereolithography 3D printing technology in pharmaceuticals: a review

3D打印 医药制造业 计算机科学 立体光刻 设计质量 工艺工程 3d打印 质量(理念) 材料科学 纳米技术 三维打印 制造工程 机械工程 工程类 运营管理 医学 哲学 认识论 药理学 下游(制造业)
作者
Subhash Deshmane,Prakash N. Kendre,Hitendra S. Mahajan,Shirish P. Jain
出处
期刊:Drug Development and Industrial Pharmacy [Taylor & Francis]
卷期号:47 (9): 1362-1372 被引量:101
标识
DOI:10.1080/03639045.2021.1994990
摘要

Three-dimensional printing (3DP) technology is an innovative tool used in manufacturing medical devices, producing alloys, replacing biological tissues, producing customized dosage forms and so on. Stereolithography (SLA), a 3D printing technique, is very rapid and highly accurate and produces finished products of uniform quality. 3D formulations have been optimized with a perfect tool of artificial intelligence learning techniques. Complex designs/shapes can be fabricated through SLA using the photopolymerization principle. Different 3DP technologies are introduced and the most promising of these, SLA, and its commercial applications, are focused on. The high speed and effectiveness of SLA are highlighted. The working principle of SLA, the materials used and applications of the technique in a wide range of different sectors are highlighted in this review. An innovative idea of 3D printing customized pharmaceutical dosage forms is also presented. SLA compromises several advantages over other methods, such as cost effectiveness, controlled integrity of materials and greater speed. The development of SLA has allowed the development of printed pharmaceutical devices. Considering the present trends, it is expected that SLA will be used along with conventional methods of manufacturing of 3D model. This 3D printing technology may be utilized as a novel tool for delivering drugs on demand. This review will be useful for researchers working on 3D printing technologies.
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