转鼓
化学
光催化
合成子
亲核细胞
电泳剂
二氧化碳
有机化学
铱
光化学
催化作用
作者
Shintaro Okumura,Yasuhiro Uozumi
出处
期刊:Organic Letters
[American Chemical Society]
日期:2021-09-01
卷期号:23 (18): 7194-7198
被引量:10
标识
DOI:10.1021/acs.orglett.1c02592
摘要
We have developed a new photocatalytic umpolung reaction of carbonyl compounds to generate anionic carbinol synthons. Aromatic aldehydes or ketones reacted with carbon dioxide in the presence of an iridium photocatalyst and 1,3-dimethyl-2-phenyl-2,3-dihydro-1H-benzimidazole (DMBI) as a reductant under visible-light irradiation to furnish the corresponding α-hydroxycarboxylic acids through nucleophilic addition of the resulting carbinol anions to electrophilic carbon dioxide.
科研通智能强力驱动
Strongly Powered by AbleSci AI