化学
部分
缬氨酸
氨基酸
苯丙氨酸
丙氨酸
立体化学
内酰胺
组合化学
生物化学
作者
Katarzyna Koroniak-Szejn,Katarzyna Salamon-Krokosz,Mateusz Gołdyn,Tomasz Siodła,Elżbieta Bartoszak-Adamska,Henryk Koroniak
出处
期刊:Synthesis
[Georg Thieme Verlag KG]
日期:2022-03-01
卷期号:54 (17): 3785-3792
标识
DOI:10.1055/s-0041-1737346
摘要
Abstract Herein, we report the synthesis of analogues of amino acids with a monofluorovinyl moiety. Interestingly, we have found that cyclization of the obtained products proceeds easily in all cases. The cyclization process has not previously been observed at this reaction stage, and such fluorinated lactams derived from phenylalanine, valine, alanine have not been described before.
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