骨肉瘤
类骨质
医学
成骨细胞瘤
病理
鉴别诊断
动脉瘤样骨囊肿
初生骨
放射科
病变
作者
Nikhil Sangle,Lester J. Layfield
出处
期刊:Archives of Pathology & Laboratory Medicine
[Archives of Pathology and Laboratory Medicine]
日期:2012-05-01
卷期号:136 (5): 572-576
被引量:60
标识
DOI:10.5858/arpa.2011-0204-rs
摘要
Osteosarcoma is one of the most common primary malignant bone tumors in children and adolescents. Telangiectatic osteosarcoma is an unusual variant of osteosarcoma, forming 3% to 10% of all osteosarcomas. Radiographically, these tumors appear as purely lytic destructive lesions located in the metaphyses of long bones. The location and x-ray appearance of telangiectatic osteosarcomas are reminiscent of an aneurysmal bone cyst and can test the acumen of a diagnostic radiologist. Distinguishing between the two entities microscopically can also be quite challenging. Telangiectatic osteosarcoma shows dilated blood-filled spaces lined or traversed by septa containing atypical stromal cells, with or without production of a lacelike osteoid matrix. This review highlights the diagnostic features of telangiectatic osteosarcoma and discusses differential diagnostic considerations, treatment options, and prognostic implications.
科研通智能强力驱动
Strongly Powered by AbleSci AI