医学
优势比
混淆
可能性
逻辑回归
多元分析
美国麻醉师学会
重症监护室
麻醉
广义估计方程
麻醉学
急诊医学
重症监护医学
内科学
数学
统计
作者
Maxim A. Terekhov,Jesse M. Ehrenfeld,Richard P. Dutton,Oscar D. Guillamondegui,Barbara J. Martin,Jonathan P. Wanderer
出处
期刊:Anesthesiology
[Lippincott Williams & Wilkins]
日期:2016-07-27
卷期号:125 (4): 690-699
被引量:56
标识
DOI:10.1097/aln.0000000000001246
摘要
Abstract Background Whether anesthesia care transitions and provision of short breaks affect patient outcomes remains unclear. Methods The authors determined the number of anesthesia handovers and breaks during each case for adults admitted between 2005 and 2014, along with age, sex, race, American Society of Anesthesiologists physical status, start time and duration of surgery, and diagnosis and procedure codes. The authors defined a collapsed composite of in-hospital mortality and major morbidities based on primary and secondary diagnoses. The relationship between the total number of anesthesia handovers during a case and the collapsed composite outcome was assessed with a multivariable logistic regression. The relationship between the total number of anesthesia handovers during a case and the components of the composite outcome was assessed using multivariate generalized estimating equation methods. Additionally, the authors analyzed major complications and/or death within 30 days of surgery based on the American College of Surgeons National Surgical Quality Improvement Program–defined events. Results A total of 140,754 anesthetics were identified for the primary analysis. The number of anesthesia handovers was not found to be associated (P = 0.19) with increased odds of postoperative mortality and serious complications, as measured by the collapsed composite, with odds ratio for a one unit increase in handovers of 0.957; 95% CI, 0.895 to 1.022, when controlled for potential confounding variables. A total of 8,404 anesthetics were identified for the NSQIP analysis (collapsed composite odds ratio, 0.868; 95% CI, 0.718 to 1.049 for handovers). Conclusions In the analysis of intraoperative handovers, anesthesia care transitions were not associated with an increased risk of postoperative adverse outcomes.
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