Viscoelastic Hydrogel with Mechanomodulatory Tension Shielding and Time‐Dependent Immunomodulatory Effects for Scarless Healing (Adv. Healthcare Mater. 32/2025)

Viscoelastic Hydrogel Viscoelastic hydrogel patch exhibits mechanomodulatory tension-shielding and time-dependent immunomodulatory effects for scarless wound healing. Namely, the matrix viscoelasticity and immune modulation work synergistically to regulate the wound healing process toward fetal-like regeneration, decreasing the likelihood of fibroblast differentiation into myofibroblasts, fostering a positive feedback loop through M2 macrophage polarization, and preventing excessive collagen deposition. More details can be found in the Research Article by Tzu-Wei Wang and co-workers (DOI: 10.1002/adhm.202501954).