医学
心脏病学
内科学
失代偿
肺动脉高压
心脏失代偿
单核苷酸多态性
生物标志物
心力衰竭
遗传倾向
肌成纤维细胞
右心室衰竭
心脏功能不全
心室重构
肺动脉
心电图
纤维化
心肌梗塞
作者
Yongneng Zhang,Sébastien Bonnet,Steeve Provencher,Jiyuan Piao,Alois Haromy,Yongsheng Liu,Yuan-Yuan Zhao,Sandra Breuils-Bonnet,Sarah‐Eve Lemay,Dawn E. Bowles,M. Mendiola,Gopinath Sutendra,Evangelos D. Michelakis
出处
期刊:Circulation
[Lippincott Williams & Wilkins]
日期:2026-03-09
标识
DOI:10.1161/circulationaha.125.078674
摘要
Our data suggest that a change of cell identity (cFBs to cMFBs) in the RV is a driver of RV decompensation. TNF-α or rs659366 is a potential biomarker for early RV decompensation in PAH.
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