An Improved Procedure forN-Formylation of Secondary Amines Using Chlorotrimethylsilane-Imidazole-N,N-Dimethylformamide

All articles of this category An improved method for the N -formylation of secondary amines using chlorotrimethylsilane and imidazole in N , N -dimethylformamide is described. The reaction conditions are tolerant of ester functional groups, and an amine hydrochloride may be N -formylated using a slight modification of the procedure.