纳米花
过氧化氢
电化学
生物传感器
材料科学
血红蛋白
纳米技术
化学
作者
Jiaojiao Gao,Hui Liu,Cheng Tong,Pang Lingyan,Yanqi Feng,Minggao Zuo,Zhiqing Wei,Li Junqi
标识
DOI:10.1016/j.snb.2019.127628
摘要
Abstract In our study, flower-like hemoglobin (Hb)-Mn3(PO4)2 hybrid nanoflowers (HMHNFs) were synthesized to generate a hydrogen peroxide (H2O2) electrochemical biosensor. Hybrid structure consisted of Hb and Mn3(PO4)2 was designed for the first time to enhance the electrochemical signal of biosensor. This new electrochemical sensing material, can efficiently catalyze the reduction of H2O2, amplify electrochemical signal and increase sensitivity. This new designed biosensor exhibited an outstanding electrochemical performance in the selective and sensitive measurement of H2O2 with an extremely low detection limit of 7 nM and the linear range was from 20 nM to 3.6 μM. The excellent H2O2-sensing performance can be attributed to the unfolding of Hb as well as the high specific surface of HMHNFs that produces opulent exposed electroactive centers for H2O2 reduction. Moreover, HMHNFs-based biosensor performed well in the measurement of H2O2 in both rainwater and human serum samples. These results indicated HMHNFs-based biosensor was a potential candidate in clinical analysis and environmental monitoring.
科研通智能强力驱动
Strongly Powered by AbleSci AI