成纤维细胞活化蛋白
医学
胰腺癌
免疫组织化学
腺癌
间质细胞
肌成纤维细胞
成纤维细胞
基质
病理
内科学
淋巴
癌症研究
纤维化
肿瘤科
癌症
生物
细胞培养
遗传学
作者
Steven J. Cohen,R. Katherine Alpaugh,Irma Palazzo,Neal J. Meropol,André Rogatko,Zhiheng Xu,John P. Hoffman,Louis M. Weiner,Jonathan D. Cheng
出处
期刊：Pancreas
[Lippincott Williams & Wilkins]
日期：2008-08-01
卷期号：37 (2): 154-158
被引量：233
标识
DOI：10.1097/mpa.0b013e31816618ce
摘要
Fibroblast activation protein is highly expressed in pancreatic adenocarcinoma, with greatest expression immediately adjacent to tumor. Higher FAP expression is associated with worse clinical outcome. The investigation of FAP inhibitors as a therapeutic strategy against pancreatic cancer should be considered.
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