乳铁蛋白
人类健康
免疫系统
糖蛋白
生物
计算生物学
生物技术
化学
生物化学
医学
免疫学
环境卫生
作者
Xiang Cao,Yang Ren,Qinyue Lu,Kun Wang,Yanni Wu,YuHao Wang,Yihui Zhang,Xiang-Shun Cui,Zhangping Yang,Zhi Chen
标识
DOI:10.3389/fnut.2022.1018336
摘要
Lactoferrin (Lf), existing widely in human and mammalian milk, is a multifunctional glycoprotein with many functions, such as immune regulation, anti-inflammation, antibacterial, antiviral, and antioxidant. These extensive functions largely attribute to its ability to chelate iron and interfere with the cellular receptors of pathogenic microorganisms and their hosts. Moreover, it is non-toxic and has good compatibility with other supplements. Thus, Lf has been widely used in food nutrition, drug carriers, biotechnology, and feed development. Although Lf has been continuously explored and studied, a more comprehensive and systematic compendium is still required. This review presents the recent advances in the structure and physicochemical properties of Lf as well as clinical studies on human diseases, with the aim of providing a reference for further research of Lf and the development of its related functional products.
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