Coronary artery calcification distribution and progression in over 70 000 asymptomatic individuals: implications for assessment intervals and optimal testing age

In a large Korean cohort of over 70 000 asymptomatic adults, most had baseline CAC = 0, indicating low subclinical atherosclerosis. Significant calcification (CAC > 100) was rare within 5-6 years, with only 4% exceeding 100 by 10 years, even among older subgroups.