外周血单个核细胞
生物
诱导多能干细胞
外周血
精神分裂症(面向对象编程)
人诱导多能干细胞
外周血干细胞
免疫学
外围设备
细胞培养
干细胞
细胞生物学
遗传学
内科学
体外
基因
胚胎干细胞
精神科
造血干细胞移植
医学
心理学
作者
Yuxing Long,Meixiang Jiang,Yiliang Liu,Ran Li,Jingyi Xu,Tongyue Chi,Menglu Sun,Miao Li,Hao Yu,Xiaobo Han
标识
DOI:10.1016/j.scr.2025.103680
摘要
We collected a blood sample from a 35-year-old male diagnosed with schizophrenia, isolated peripheral blood mononuclear cells, and generated a human induced pluripotent stem cells (hiPSCs) line using non-integrative reprogramming techniques. The derived cells exhibit characteristics typical of embryonic stem cells, are capable of expressing specific pluripotency markers, and can differentiate into all three embryonic layers in vitro. This iPSCs line serves as an in vitro model for investigating disease mechanisms and for developing novel therapeutic approaches.
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