Sequential Paired Electrolysis-Enabled Synthesis of Antifungal-Active gem-Difluoroalkenes via Electrochemical Halogen Atom Transfer

Fluorine-containing compounds, particularly gem-difluoroalkenesrecognized as bioisosteres of carbonyl groups-hold crucial value in pharmaceuticals, agrochemicals, and functional materials, as they can modulate drug molecules' lipophilicity, pKa, and bioavailability. Alkyl halides, indispensable...