清脆的
基因组编辑
遗传学
基因
生物
同源(生物学)
计算生物学
同源定向修复
Cas9
DNA修复
核苷酸切除修复
作者
Hongyu Liao,Jiahao Wu,Nathan J. VanDusen,Yifei Li,Yanjiang Zheng
标识
DOI:10.1016/j.omtn.2024.102344
摘要
gene therapies. Finally, we discuss alternative precise editing platforms and their limitations, and describe potential avenues to improving CRISPR-Cas9-mediated HDR efficiency and fidelity in future research.
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