Cu(II)/polyimide linked COF: An effective mesoporous catalyst for solvent-free 1,5-benzodiazepine synthesis

Copper(II)@polyimide linked covalent organic frameworks ([email protected]) under solvent-free and microwave assisted conditions have been used in an efficient one-pot protocol for the preparation of 1,5-benzodiazepines via 1,2-diaminobenzene, aromatic aldehydes and dimedone. By applying solvent-free conditions and microwave irradiation, three-component condensation provides safe operations, low pollution, quick access to products, and an easy set-up. As a result of its reusability, the catalyst can also be reutilized many runs without missing any activity.