间充质干细胞
冲程(发动机)
炎症
医学
骨髓
干细胞
干细胞疗法
神经科学
病理
免疫学
生物信息学
生物
细胞生物学
机械工程
工程类
作者
Ming Jiang,Yidong Liao,Wenxue Song,Zili Wang,Junshuan Cui,Longcai He,Guangtang Chen,Kaya Xu
标识
DOI:10.1016/j.brainres.2024.148964
摘要
Stem cell therapy has become a hot research topic in the medical field in recent years, with enormous potential for treating a variety of diseases. In particular, bone marrow mesenchymal stem cells (BMSCs) have wide-ranging applications in the treatment of ischemic stroke, autoimmune diseases, tissue repair, and difficult-to-treat diseases. BMSCs can differentiate into multiple cell types and exhibit strong immunomodulatory properties. Although BMSCs can regulate the inflammatory response activated after stroke, the mechanism by which BMSCs regulate inflammation remains unclear and requires further study. Recently, stem cell therapy has emerged as a potentially effective approach for enhancing the recovery process following an ischemic stroke. For example, by regulating post-stroke inflammation and by transferring mitochondria to exert therapeutic effects. Therefore, this article reviews the therapeutic effects of intracranial BMSCs in regulating post-stroke inflammation and mitochondrial transfer in the treatment of stroke, providing a basis for further research.
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