Objective: To explore the effect of remifentanil combined with sevoflurane on pediatric anesthesia emergence delirium( PAED). Methods: Sixty children of tonsillectomy,aged 4 to 7 years old and grade ASA I,were randomly divided into experimental group( remifentanil plus sevoflurane group) and control group( sevoflurane group),30 cases in each group. The operation time,the anesthesia recovery time and the agitation scores in two groups were recorded. Results: The agitation cases,agitation proportion and the cases whose agitation time was more than 15 min in remifentanil plus sevoflurane group was significantly less than the counterparts in control group( P 0. 05); There was no significant difference in operation time and anesthesia recovery time for two groups( P 0. 05).Conclusion: The anesthesia method of remifentanil combined with sevoflurane is better than sevoflurane anesthesia in children tonsillectomy surgery.