Current Status of Prevention of Pancreatic Fistula after Pancreaticoduodenectomy

Objective To evaluate the various methods in prevention of pancreatic fistula after pancreaticoduodenectomy.Methods The literatures over the years related to prevention of pancreatic fistula were reviewed.Results Management of the pancreatic stump following pancreaticoduodenectomy played the most important role in preventing pancreatic fistula. None of the methods of pancreatic stump had proved to be perfect in preventing pancreatic fistula, though pancreaticojejunostomy was the most widely practiced reconstruct strategy in varieties of option. For pancreaticojejunostomy and pancreaticogastrostomy, the rate of this complication was 12.3% and 11.1%,respectively. In recent years, a new procedure, binding up pancreaticoduodenectomy, had shown a promise and excellent results in prevention of pancreatic fistula, the rate of fistula was 0 for consecutive 100 cases after pancreaticoduodenectomy.Conclusion Binding up pancreaticojejunostomy have a definite effect to avoid pancreatic fistula and be worthy of being recommended