The Clinical Significance of Combined Testing of Plasma Fibrinogen and D-dimer in Pulmonary Embolism Patients

Objective To investigate the role of combined testing of plasma fibrinogen and D-dimer in pulmonary embolism patients. Methods The plasma fibrinogen and D-dimer in pulmonary embolism patients were measured. The differences between the patients and the normal individuals were studied by T test. Results The concentration of plasma fibrinogen and D-dimer were increased significantly in patients with pulmonary embolism group (P 0.01), and were decreased after treatment (P 0.01). The difference was remarkable, especially in the patients with effective therapy (P 0.01). Conclusion Our primary result indicates that the changes of fibrinogen and D-dimer are important parameters for the judgment of the treatment efficacy of pulmonary embolism.