Objective Analyze the scan program of liver CT perfusion imaging,the calculation of perfusion parameter and the reconstruction method of perfusion parameters image.Methods In October of 2011,select 25 volunteers with normal liver function as the research objects,scan the liver CT perfusion imaging,calculate the perfusion parameter and reconstruct the image.Results Apply film scan with breathholding,calculate the time immediately after injecting contrast agents,wait 7~9s for a continuous scanning with total time of 45s for 45 layers,obtain the expected images,reconstruct the images with software and finally get good application effect.Conclusion the application of CT perfusion imaging in liver or other diseases scanning has obvious advantages than other imaging examination methods,but it also has certain restrictions.