特应性皮炎
医学
维生素D与神经学
哮喘
免疫学
过敏
免疫系统
维生素D缺乏
皮肤病科
内科学
作者
Daniel A. Searing,Donald Y.M. Leung
标识
DOI:10.1016/j.iac.2010.05.005
摘要
This review examines the scientific evidence behind the hypothesis that vitamin D plays a role in the pathogenesis of allergic diseases , along with a focus on emerging data regarding vitamin D and atopic dermatitis . Elucidated molecular interactions of vitamin D with components of the immune system and clinical data regarding vitamin D deficiency and atopic diseases are discussed. The rationale behind the sunshine hypothesis, laboratory evidence supporting links between vitamin D deficiency and allergic diseases, the clinical evidence for and against vitamin D playing a role in allergic diseases, and the emerging evidence regarding the potential use of vitamin D to augment the innate immune response in atopic dermatitis are reviewed.
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