Production of Antifungal and Antibacterial Substances by Fungi; Preliminary Examination of 166 Strains of Fungi Imperfecti

SUMMARY: One hundred and sixty-six strains of Fungi Imperfecti have been examined primarily for the production of antifungal substances, though antibacterial substances have also been sought in most cases. Antifungal substances were produced by several species of Aspergillus and Penicillium, Fusarium caeruleum, Metarrhizium glutinosum, Stachybotrys atra, Tri-choderma viride, Gliocladium catenulatum and Trichothecium roseum. Antibacterial substances were produced by species of Aspergillus, Fusarium, Penicillium, Stachybotrys and Trichoderma. The chemical nature of the substances responsible for this activity is known or can be suggested in some cases, but others are worthy of further investigation.