医学
放射外科
外科
假性动脉瘤
并发症
放射治疗
颈内动脉
肢端肥大症
经蝶手术
Pegvisomant公司
垂体腺瘤
腺瘤
内科学
激素
生长激素
作者
Ana Cláudia Oliveira Carreira,Solomon Muna,Ashley Grossman,Márta Korbonits
出处
期刊:Case Reports
[BMJ]
日期:2024-04-01
卷期号:17 (4): e258533-e258533
标识
DOI:10.1136/bcr-2023-258533
摘要
We present a fatal complication of treatment in a patient with early-onset acromegaly, treated with two transsphenoidal operations, radiotherapy, radiosurgery and pegvisomant. He was diagnosed in his 30s, and controlled from his 40s, with stable residual tumour within the left cavernous sinus. In his 60s, 30 years after surgery/radiotherapy and 14 years after radiosurgery, he developed recurrent episodes of mild epistaxis. A week later, he presented at his local hospital’s emergency department with severe epistaxis and altered consciousness. He was diagnosed with a ruptured internal carotid artery (ICA) pseudoaneurysm, but unfortunately died before treatment could be attempted. ICA pseudoaneurysms are rare complications of surgery or radiotherapy and can present with several years of delay, often with epistaxis. This case highlights the importance of life-long monitoring in patients with previous pituitary interventions and early recognition of epistaxis as a herald sign of a potentially catastrophic event, thus leading to timely treatment.
科研通智能强力驱动
Strongly Powered by AbleSci AI