医学
皮肤癌
随机对照试验
焦虑
入射(几何)
剂量计
临床试验
皮肤病科
生活质量(医疗保健)
癌症
内科学
核医学
精神科
护理部
剂量学
物理
光学
作者
Emmanuel L. P. Dumont,Peter D. Kaplan,Catherine Do,Shayak Banerjee,Melissa Barrer,Khaled Ezzedine,Jonathan Zippin,George I. Varghese
标识
DOI:10.3389/fmed.2024.1259050
摘要
Background Non-melanoma skin cancer (NMSC) is the most prevalent cancer in the United States. Despite guidelines on ultraviolet (UV) avoidance, it remains difficult for people to assess their exposure, as UV is invisible and the onset of UV-induced symptoms is delayed. Methods In a prospective randomized trial, 97 elderly patients with a history of actinic keratoses (AK) were followed over 6 months. Fifty patients received UV counseling from a dermatologist and a wearable UV dosimeter that provided real-time and cumulative UV exposure. Forty-seven patients received only UV counseling from a dermatologist. Results Over 75% of participants recorded UV exposure at least once a week during the summer. After 6 months of intervention, when comparing the device group to the control group, we observed a non-significant 20% lower ratio of incidence rates of AKs (95% CI = [−41, 55%], p -value = 0.44) and a significant 95% lower ratio of incidence rates of NMSCs (95% CI = [33, 99.6%], p -value = 0.024). Surveys demonstrated that the control group’s score in self-perceived ability to participate in social activities significantly increased by 1.2 ( p -value = 0.04), while in the device group, this score non-significantly decreased by 0.9 ( p -value = 0.1). We did not observe changes, or between-group differences, in anxiety and depression surveys. Conclusion This pilot clinical trial has a short duration and a small sample size. However, device adherence and quality of life questionnaires suggest a smartphone-connected wearable UV dosimeter is well accepted by an elderly population. This trial also indicates that a wearable UV dosimeter may be an effective behavioral change tool to reduce NMSC incidence in an elderly population with a prior history of AKs. Clinical trial registration : clinicaltrials.gov , identifier NCT03315286.
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