免疫抑制
免疫系统
调节性T细胞
Treg细胞
自我容忍
免疫耐受
调节性B细胞
医学
自身免疫
生物
T细胞
免疫学
白细胞介素10
白细胞介素2受体
作者
Patrick Ho,Ellen Cahir-McFarland,Jason D. Fontenot,Tracey Lodie,Adel Nada,Qizhi Tang,Laurence A. Turka,Jeffrey A. Bluestone
标识
DOI：10.1126/scitranslmed.adm8859
摘要
Engineered regulatory T (T reg ) cells have emerged as precision therapeutics aimed at inducing immune tolerance while reducing the risks associated with generalized immunosuppression. This Viewpoint highlights the opportunities and challenges for engineered T reg cell therapies in treating autoimmune and other inflammatory diseases.
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