免疫抑制
免疫系统
调节性T细胞
Treg细胞
自我容忍
免疫耐受
调节性B细胞
医学
自身免疫
生物
T细胞
免疫学
白细胞介素10
白细胞介素2受体
作者
Patrick Ho,Ellen Cahir-McFarland,Jason D. Fontenot,Tracey Lodie,A. A. Nada,Qizhi Tang,Laurence A. Turka,Jeffrey A. Bluestone
出处
期刊：Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期：2024-03-13
卷期号：16 (738)
标识
DOI：10.1126/scitranslmed.adm8859
摘要
Engineered regulatory T (Treg) cells have emerged as precision therapeutics aimed at inducing immune tolerance while reducing the risks associated with generalized immunosuppression. This Viewpoint highlights the opportunities and challenges for engineered Treg cell therapies in treating autoimmune and other inflammatory diseases.
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