脑炎
医学
病因学
鉴别诊断
记事
疾病
临床诊断
免疫学
病毒
病理
儿科
内科学
作者
Olga O. Rzhevska,Л.А. Ходак,Antonina I. Butenko,T.M. Kvaratskheliya,K. V. Shtrakh,Anatolii M. Shevchuk,Yurii B. Yashchenko
出处
期刊:Wiadomości lekarskie (Warsaw Poland)
[ALUNA]
日期:2023-01-01
卷期号:76 (10): 2263-2268
被引量:1
标识
DOI:10.36740/wlek202310120
摘要
The aim: To investigate the clinical characteristics of EBV infection in the pediatric nervous system using laboratory methods and brain MRI data.Materials and methods: We observed 41 children with EBV encephalitis ranging from 8 months to 17 years old. The diagnosis of EBV-encephalitis was established on the basis of clinical and medical history, laboratory and instrumental (brain MRI) data. The main thing in the diagnosis was clinical symptoms, combining general infection, cerebral syndromes and focal neurological symptoms. The etiology of Epstein-Barr virus was determined using ELISA and PCR.Results: EBV-encephalitis can be as a manifestation of reactivation of persistent EBV infection (85%), much less often - acute primary EBV infection (15%). By nature, the duration of EBV encephalitis has distinguished two forms of its course: acute (63%) and chronioc (37%). The criteria of differential diagnosis of acute and chronic forms of EBV-encephalitis are proposed, which include the most common anamnesis data, clinical manifestations and changes in brain MRI.Conclusions: The proposed criteria specifically for acute and chronic forms of EBV-encephalitis can contribute to the timely and more accurate diagnosis of this disease in children.
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