The Role of Comprehensive Structural Preservation Strategy in Skull Base Reconstruction Following Endoscopic Endonasal Surgery for Pituitary Neuroendocrine Tumors: A Retrospective Single-Center Study

The CSP-TSA demonstrated equivalent efficacy in tumor resection and functional outcomes compared to TNA, while significantly reducing postoperative CSF leakage and overall complication rates. The protective reconfiguration of the anterior wall of the sphenoid sinus, in-situ bone flap of the sellar floor, and sphenoid mucosal flap may enhance skull base reconstruction in CSP-TSA, highlighting its potential as a superior strategy for structural preservation in EES for PitNETs.